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It’s about time someone devised a good method for integrating existing transcriptome and miRNAome collections into a network of functional predicted functional interactions, as well as miR-mRNA target prediction based on sequence and anticorrelation.
Which makes it even more unfortunate that they pulled an “Pujols-on-a-hit-and-run”-esque whiff on presenting their results. Yes, the complexity is staggering, but the the manuscript, and especially some of the early figures, were borderline impenetrable.
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It’s about time someone devised a good method for integrating existing transcriptome and miRNAome collections into a network of functional predicted functional interactions, as well as miR-mRNA target prediction based on sequence and anticorrelation.

Which makes it even more unfortunate that they pulled an “Pujols-on-a-hit-and-run”-esque whiff on presenting their results. Yes, the complexity is staggering, but the the manuscript, and especially some of the early figures, were borderline impenetrable.

Source: cell.com

    • #Califano
    • #cell
    • #miRNAs
    • #cancer
    • #glioblastoma
  • 1 year ago
  • 51
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Copyright R Borkowski. Logo from Sumazin, P. et al. An Extensive MicroRNA-Mediated Network of RNA-RNA Interactions Regulates Established Oncogenic Pathways in Glioblastoma. Cell 147, 370–381 (2011).

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